Cisplatin induced hypocalcemia

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WebCisplatin-induced hypomagnesemia with seizures: a case report and review of the literature Gynecol Oncol. 1988 May;30(1):104-13. doi: 10.1016/0090-8258(88)90052-2. Authors S L Bellin 1 ... Hypocalcemia / chemically induced Hypokalemia / … WebMay 24, 2006 · Cisplatin is the most commonly used antineoplastic agent for the treatment of solid tumors and is a well-known cause of nephrotoxicity [ 1 ]. In this study we report a case with chronic hypokalemic metabolic alkalosis with hypomagnesemia and hypocalciuria 20 years after the initial treatment with cisplatin therapy.

Cisplatin induced hyponatremia; looking deeper - Renal Fellow …

WebHypomagnesemia is a common side effect of cisplatin occurring . in 90% of patients by the fourth cycle of treatment caused by renal tubular damage leading to increased renal … WebApr 10, 2024 · Med-Surg Nursing. Hypocalcemia is when there are low levels of calcium in the blood. Calcium is an electrolyte that plays a vital role in many bodily functions, including muscle contraction, nerve transmission, and bone formation. Various factors, including nutritional deficiencies, medications, and underlying medical conditions, can all lead ... chivas regal fish chopping board

Cisplatin induced hyponatremia; looking deeper - Renal Fellow …

WebNov 7, 2012 · The cisplatin-induced increase of the Kim-1 expression level suggests that the PST segment is also affected in our study [30, 44]. The NHE3 expression levels were similar in the kidneys of control and cisplatin-treated groups. ... Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the … WebMar 17, 2016 · It is likely that cisplatin contributed to the profound hypocalcemia in this patient, who presented with a serum Mg of 0.7 mg/dL. Denosumab, a monoclonal … WebCisplatin is a common cause of hypomagnesemia and hypokalemia due to renal magnesium (Mg) and potassium (K) losses. Magnesium plays an important role in the maintenance of intracellular K. An unrecognized and untreated Mg depletion can lead to a refractory K repletion. grasshoppers shoes black

Cisplatin and hypomagnesemia - ScienceDirect

Cisplatin induced hypocalcemia

Cisplatin induced hyponatremia; looking deeper - Renal Fellow …

WebMar 9, 2024 · Cisplatin is a clinically advanced and highly effective anticancer drug that is used for the treatment of various solid tumors, such as lung cancer, stomach cancer, and ovarian cancer [1]. However, nephrotoxicity is the … WebCisplatin is a well-known chemotherapeutic agent that can be associated with hyponatremia. Mechanisms of cisplatin-induced hyponatremia include renal salt wasting syndrome (RSWS), and the syndrome of inappropriate antidiuretic hormone secretion (SIADH) (Cheng et al., 2011 ).

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WebApr 5, 2024 · causes of hypocalcemia Severe inflammation (sepsis, major burns). Pancreatitis (especially: hypertriglyceridemic pancreatitis). Citrate (massive transfusion, plasmapheresis, leukapheresis, renal replacement therapy). Ethylene glycol poisoning. Alkalosis: Respiratory alkalosis (e.g., panic-induced). http://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Cisplatin_monograph.pdf

WebHypocalcemia is uncommon and has been attributed to hypomagnesemia resulting from use of a chemotherapeutic regimen. Very few publications have described … WebThese effects are due to renal tubular damage. Cisplatin greatly increases the urinary excretion of magnesium and calcium; increased excretion of potassium, zinc, copper and …

WebMar 22, 2024 · They exert their main toxic effect within the tubular cell by altering phospholipid metabolism. In addition to their direct effect on cells, aminoglycosides cause renal vasoconstriction. The 2... http://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Cisplatin_monograph.pdf

WebJul 18, 2024 · Cisplatin causes hypomagnesemia in a dose-dependent fashion and affects up to 90% of patients if no preventive measures are taken (see Section 5 below). 79 The etiology of cisplatin-induced hypomagnesemia is not completely understood; renal Mg loss is the primary mechanism, but gastrointestinal losses have also been reported. 80 …

WebJul 18, 2024 · Cisplatin causes hypomagnesemia in a dose-dependent fashion and affects up to 90% of patients if no preventive measures are taken (see Section 5 below). 79 The … grasshoppers shoes clearanceWebJul 18, 2024 · Cisplatin causes hypomagnesemia in a dose‐dependent fashion and affects up to 90% of patients if no preventive measures are taken (see Section 5 below). 79 The etiology of cisplatin‐induced hypomagnesemia is not completely understood; renal Mg loss is the primary mechanism, but gastrointestinal losses have also been reported. 80 ... grasshoppers scientific nameWebmannitol, or furosemide-induced diuresis is used t o effectively decrease cisplatin-induced nephrotoxicity. 7. Lower doses of cisplatin are given with less intensive hydration. For example, patients receiving doses of 35 mg/m. 2 . ... hypocalcemia may become symptomatic, with muscle irritability or cramps, clonus, tremor, carpopedal spasm and ... chivas regal jewelers st thomasWebApr 5, 2024 · In severe hypocalcemia, IV calcium is used initially, with transition to oral calcium. For mild hypocalcemia, oral calcium could be used for initial treatment. 1 gram … grasshoppers school shoesWebElectrolyte disorders with platinum-based chemotherapy: mechanisms, manifestations and management. Platinum chemotherapy, particularly cisplatin, is commonly associated with … chivas regal price at checkersWebJul 24, 2024 · Cisplatin, a chemotherapeutic drug, can also cause hypocalcemia through hypomagnesemia. Foscarnet can cause hypocalcemia by forming complexes with ionized calcium, thereby reducing levels of ionized calcium. It is therefore important to regularly monitor calcium levels during treatment with all of the above-mentioned drugs. [8] [9] grasshoppers rufcWebFeb 17, 2024 · A number of drugs sometimes cause hypocalcemia as a side effect. Some of these include the following: Certain drugs for osteoporosis ( bisphosphonates like zoledronate) 5 Some antiepileptic drugs Certain chemotherapy drugs (like cisplatin) Diuretic drugs (like furosemide) 6 Proton pump inhibitors chivas regal date on bottle