Citrate transporter family protein
WebThe citrate carrier (CiC), a nuclear-encoded protein located in the mitochondrial inner membrane, is a member of the mitochondrial carrier family. CiC plays an important role … WebAbstract. Citrate, an organic trivalent anion, is a major substrate for generation of energy in most cells. It is produced in mitochondria and used either in the Krebs' cycle or released …
Citrate transporter family protein
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WebTricarboxylate transport protein, mitochondrial, also known as tricarboxylate carrier protein and citrate transport protein (CTP), is a protein that in humans is encoded by … WebDec 15, 2024 · Iacobazzi et al. (1997) determined that the open reading frame of the human citrate transporter gene encodes a mature protein of 298 amino acids and a …
WebSLC13A5. Solute carrier family 13 (sodium-dependent citrate transporter), member 5 also known as the Na+/citrate cotransporter or mIndy is a protein that in humans is encoded by the SLC13A5 gene. [5] It is the mammalian homolog of the fly Indy gene . WebThis gene encodes a member of the mitochondrial carrier subfamily of solute carrier proteins. Members of this family include nuclear-encoded transporters that translocate …
WebThis gene encodes a sodium-driven citrate transport protein named NaCT. Disease-causing mutations abolish the uptake of citrate in neurons of the brain. ... (NaDC) from the SLC13 family. A number of mutations have been identified in the NaCT transporter gene (SLC13A5) in patients with epileptic encephalography. The Pajor Lab explores what … WebMar 1, 2024 · The Mitochondrial Carrier Family. With 53 members, the mitochondrial carrier family (solute carrier family 25, SLC25) is the largest solute transporter family in humans. They transport solutes across the impermeable inner membrane of mitochondria for important cellular processes, such as oxidative phosphorylation of fats and sugars, …
WebJan 22, 2024 · The mitochondrial citrate/isocitrate carrier, CIC, has been shown to play an important role in a growing list of human diseases. CIC belongs to a large family of nuclear-encoded mitochondrial transporters that serve the fundamental function of allowing the transit of ions and metabolites through the impermeable mitochondrial membrane.
how do you charge a samsung remoteWebFeb 12, 2024 · As the prototype for the TTT family, the TctC citrate transporter was first described by Sweet et al. (1979) in the pathogen Salmonella typhimurium, one of the most important causative agents of food-borne gastrointestinal infections and a growing problem due to the recent emergence of multidrug resistant strains (Hur et al., 2012). how do you charge a razor dirt bikeWebJan 20, 2024 · Moreover, mutations of a member of the citrate transporter family in fruit fly, INDY, promote longevity, ... Inhibitors of the mitochondrial citrate transport protein: validation of the role of ... how do you charge a smart watchWebMay 14, 2024 · The citrate transport activity of the protein was studied in CT reconstituted liposomes. Our results showed high efficiency of CT for [ 14 C] citrate/citrate exchange with K m 0.01 mM at 25°C. how do you charge a samsung galaxy s22 ultraWebJul 1, 2007 · The cellular transport of long-chain fatty acids (LCFAs) across the plasma membrane has long been thought to occur via passive diffusion. However, in recent years a substantial body of literature has emerged indicating that LCFA uptake into muscle cells occurs via a protein-mediated process (for review see Bonen et al. 2002; Luiken et al. … how do you charge a rv air conditionerWebProtein family/group databases. TCDB. 2.A.29.7.1 the mitochondrial carrier (mc) family; Names & Taxonomy. Protein names ... Citrate carrier 1 publication (CIC 1 publication) … how do you charge a vegcoo mouseWebOct 29, 2024 · Summary. This gene encodes a member of the mitochondrial carrier family. The encoded protein is responsible for the movement of tricarboxylates, such as citrate, across the inner mitochondrial membrane. It is essential to the bioenergetics of hepatic cells, supplying the cytoplasm with a carbon source for fatty acid and sterol biosynthesis, and ... how do you charge a samsung a13