Webb13 feb. 2024 · 该研究于2024年2月1日以: Slow TCA flux and ATP production in primary solid tumours but not metastases 为题,发表于 Nature 期刊。. 在细胞中,ATP可以通过 … Webb5 mars 2011 · Slow TCA flux and ATP production in primary solid tumours but not metastases. Nature - As solid tumours develop, cancer cells shed energetically expensive tissue-specific functions, enabling uncontrolled …
Slow TCA flux implies low ATP production in tumors
Webb5 feb. 2024 · As expected, glycolysis flux is increased in tumours compared with healthy tissues (the Warburg effect2,3), but this increase is insufficient to compensate for low TCA flux in terms of ATP production. Thus, instead of being hypermetabolic, as commonly assumed, solid tumours generally produce ATP at a slower than normal rate. Webb8 feb. 2024 · 通过研究血液吸收营养物质进入tca循环的速度,研究人员能够量化癌组织与健康组织相比产生和使用的能量。 例如,在肺癌、胰腺癌和结肠癌中,他们发现在“原发 … bird gyms \\u0026 playstands
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WebbSlow TCA flux and ATP production in primary solid tumours but not metastases Nature 2024-02-09 Journal article DOI: 10.1038/s41586-022-05661-6 Contributors : Caroline R. Bartman; Daniel R. Weilandt; Yihui Shen; Won Dong Lee; Yujiao Han; Tara TeSlaa; Connor S. R. Jankowski; Laith Samarah; Noel R. Park; Victoria da Silva-Diz et al. WebbTCA flux and ATP production in primary solid tumors, but not metastases, are slower than healthy tissue. ... Primary Solid Tumors Have Slow TCA Flux and ATP Production Cancer … Webb2 feb. 2024 · In lung, pancreatic, and colon cancers, for example, they found a slow TCA flux and ATP production cycle in “primary” solid tumors, i.e. tumors that had not yet … bird green conure